Here, we show that conolidine, a organic analgesic alkaloid used in classic Chinese medicine, targets ACKR3, therefore delivering additional evidence of the correlation involving ACKR3 and discomfort modulation and opening alternative therapeutic avenues for the treatment method of Serious discomfort. We shown that, in contrast to classical opioid receptors, https://aarona061tkz7.jasperwiki.com/user