At an oral dose of 2000 mg/kg/working day in rats, maternal toxicity and deaths had been found with an increased incidence of early fetal resorption; spontaneous abortions happened in cynomolgus monkeys for the maternally harmful oral dose of 2000 mg/kg/day; there isn't any enough and properly-controlled trials in Expecting women; https://as-8546790.blazingblog.com/34401348/fsg67-things-to-know-before-you-buy