You will find there's launch of norepinephrine with the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors during the dorsal horn to lower afferent pain transmission and create analgesia. For that reason, medication like clonidine that focus on alpha-two receptors can impact the transmission of ache. Jun 10, 2024 https://johno738neu4.wikilinksnews.com/user